Mikroreaktory vyrobené 3D tiskem

Abstract

The development and subsequent manufacturing of microreactors using FDM 3D printing technology and applying these printed microreactors for the synthesis of silver nanoparticles were the main topics of this thesis. The work is divided into a theoretical part, an experimental part, and results. The work's theoretical part is divided into several thematic areas, which are closely related to the development of microreactors using 3D printing and their subsequent applications for the synthesis of silver nanoparticles. The first thematic area is focused on the physical properties of microreactors, their advantages, disadvantages, and uses. Attention is also paid to mixing and transport phenomena, which are characteristic in microscale. Another thematic area is focused on nanotechnologies, biosynthesis of nanoparticles, and their use. The last thematic is focused on additive manufacturing, mainly to the principle, methods of 3D printing, and the current state of knowledge in 3D printing of microreactors. The experimental part consists of several main points. The first point is focused on microreactors, their design, construction, and manufacturing of two microreactors types – MZ2R and VZ2R by the 3D printing and then analysis of these microreactors by the computed tomography. Another point is to design and subsequent manufacturing 3D printed syringe pumps, which are used to fill liquids into microreactors. The third point is an assembly and detailed description of the microfluidic apparatus, including analytical methods. The last point is the biosynthesis of silver nanoparticles using 3D printed microreactors and subsequent analysis of the produced nanoparticles by UV-VIS spectrophotometry and scanning transmission electron microscopy. The properties of 3D-printed microreactors and the results from the analysis of prepared nanoparticles are discussed in the final part of the work.