Nanokompozitní organojílové materiály s antimikrobiální účinností

Abstract

This bachelor thesis is focused on the preparation and characterization of organoclay nanocomposite materials with antimicrobial activity, when active antimicrobial ingredient is an antifungal ciclopiroxolamine. Two series of samples were prepared. In the first case clay mineral vermiculite was used as the supporting matrix and secondly clay mineral bentonite was used. The structure of the prepared samples was characterized by X-ray diffraction analysis (XRD), infrared spectroscopy (IR) and scanning electron microscope (SEM). Furthermore, the content of organic carbon was determined in the composite samples. Antimicrobial activity of nanocomposites was tested against bacterial strains Staphylococcus aureus and Escherichia coli, and against yeast Candida albicans and it was evaluated by finding minimum inhibitory concentration (MIC).