Antimicrobial properties of biosynthesized metallic nanoparticles

Abstract

This bachelor thesis devotes to the study of antimicrobial properties of the bionanocomposite consists of gold and silver nanoparticles biosynthesized on the siliceous frustule of diatoms. The theoretical part deals with the biosynthesis of gold and silver nanoparticles and the principle of antimicrobial properties of these particles against a wide range of bacteria or fungi. The aim of the experimental part is the implementation of the biosynthesis of gold and silver nanoparticles with a diatom species Diadesmis gallica and subsequent realization of the antibacterial tests against three selected bacterial species. The prepared bionanocomposite was also characterized by transmission electron microscopy containing also particle size distribution image analysis, atomic absorption spectrometry and X-RAY powder diffraction. In conclusion, the possible applications of biosynthesized composite with antimicrobial properties are discussed.