Vztah mezi atmosférickými polutanty z průmyslu a výskytem diabetes mellitus

Abstract

The dissertation thesis discusses the relationship between atmospherically contaminants originated from industry and local fire-boxes and diabetes and its complications in the territory of European region. Nowadays, atmospheric contaminants represent a significant factor of the environment of man. This fact especially concerns the low-developed countries. The atmospheric contaminants become a part of air pollution and through the various way of exposition, they can come into interaction with human organism. The final effect of this interaction is a negative health impact. Atmospherically contaminants can initiate plenty miscellaneous diseases and pathological states. In population exposed to harmful effects of pollutants, this fact will demonstrate through rising trend of incidence of diseases and through the elevation of numbers of total morbidity and mortality. Diabetes and its complications belong among diseases with rising abundance in continuity with contaminated environment. The hypothetic association between parameters of diabetes (incidence, mortality connected with diabetes) and some atmospheric contaminants was verified in this dissertation thesis too. Among pollutants with impacts onto parameters discussed above, the following spectrum of atmospherically pollutants belongs – i. e. some fraction of particulate matter (PM10, PM2,5), nitrogen oxides (NOx), tropospheric ozone (O3), benzo(a)pyrene (BaP) and sulphur dioxide (SO2). The validity of this association was confirmed for the case of European countries and also for the regions of the Czech Republic. Dominant sources of air pollution emitting PM2.5 affecting the prevalence of DM and its complications in European countries include local space heating (54% of emissions), transport (12.7% of PM2.5, 47% of NOx emissions), energy (2.7% of PM2.5, 14% of NOx) and industrial production (17% of PM2.5 emissions, 42% of NMVOC emissions). The elimination of the PM2.5 burden appears to be a major problem also in relation to the current energy situation, or crisis. With the goal of prevention of diabetes and its complications, it is necessary to realize monitoring of all potential associations between mentioned disease and environmental contaminants, respectively pollutants. This dissertation thesis should also contribute to purpose discussed above.