Cílení stereotaktické radioterapie komorových tachykardií pomocí fúze elektroanatomických map a CT modelů

Abstract

In this paper, a new methodology for left ventricular scar targeting is proposed based on extraction of system data from the electroanatomical mapping system and subsequent conversion into visualized models using the developed software. These models are then combined with segmented models from CT DICOM images, and arrhythmogenic scars are marked in a special graphical editor and exported in DICOM format for use in the radiologist's workstation. Evaluation of the results of the proposed methodology was performed objectively using DICE parameters and the mean Hausdorff distance. Further evaluation was performed by manual and automated measurement of 2D images of the original and generated volume of arrhythmogenic substrates. The results of this work show that the proposed methodology achieves a high level of accuracy in targeting the arrhythmogenic substrate (mean DSC = 0.86, SD = 0.26, mean Hausdorff distance = 1.81 mm, SD = 0.25 for intraobserver variability and mean DSC = 0.86, mean Hausdorff distance = 1.36 mm, for interobserver variability). The result of this work is a methodology that is an effective tool for improving the accuracy and speed of targeting arrhythmogenic foci in patients undergoing this therapy.