Biodegradable, pH-responsive chitosan aerogels for biomedical applications

Abstract

Novel pH-responsive biodegradable chitosan aerogels for biomedical applications were developed. Prepared from propylene glycol and bioactive acids under MW conditions hydrogels were transformed into aerogels by lyophilisation. Obtained materials were characterized with FT-IR spectroscopy and SEM imaging. Biodegradability, bioactivity and pH response were analysed. An anticancer drug release profile was investigated.