Analýza pohyblivých cílů v radioterapii a zhodnocení vlivu na přesné dodání terapeutické dávky robotickým ozařovačem

Abstract

The topic of thesis is the analysis of targets which move with respiration during radiotherapy and evaluation of the impact of movement on dose delivery accuracy in cases when online tracking cannot be used. In these cases the patient position is tracked according to position of spine structures and irradiated volume includes the whole area of target range of movements. Analysis of moving targets uses data of patients treated with online tracking at University hospital Ostrava and provides new findings about patterns of lung tumors motion. These findings and real tumor motion data from the treatment were used to create a predictive model for intafraction variability and to test the accuracy of prescribed dose delivery to the target using film dosimetry.