Formát SAM - reprezentace a mapování sekvencí DNA

Abstract

The aim of this thesis is to implement a program that converts already mapped DNA sequences into SAM format. At the input of the program there will be DNA sequences with already assigned coordinates. These sequences will be aligned by Needleman-Wunsch algorithm and the mandatory attributes defined in the SAM format specification will be added to each of these sequences. Especially CIGAR string and consequently mapping quality.

Description

Subject(s)

SAM, CIGAR, read, alignment, base, quality

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