Dynamical properties of the improved FK3V heart cell model

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Wiley

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Abstract

The main aim of this paper is to study the evolution of the transmembrane potential on the cardiac cell under different rates and amplitudes of stimulation. For modeling this potential, the modification of the Fenton-Karma model was applied. It is a phenomenologicalmodel with 3 degrees of freedom that corresponds to nondimensional transmembrane potential and gating variables for regulation of inward and outward ion currents that can better reproduce the shape of the transmembrane potential than the original Fenton-Karma model. The model was newly forced by stimulus with the shape of the half-sine period. As the main goal of the paper is to show that this model is showing regular as well as irregularmotion; periodic and chaotic patterns are detected using bifurcation diagrams, the Fourier spectra, Poincare sections, and 0-1 test for chaos.

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bifurcation, cardiac cell model, Fourier spectra, 0-1 test for chaos

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Mathematical Methods in The Applied Sciences. 2018, vol. 41, issue 17, special issue, p. 7472-7480.