Activity of antibacterial compounds immobilised on montmorillonite

Abstract

The activities of antibacterial compounds, such as cetylpyridinium (CP), cetyltrimethylammonium (CTA), silver ions and metallic silver, immobilised on montmorillonite (MMT), were tested in Escherichia coli and Enterococcus faecium bacteria. The results of bacterial growth tests were confirmed by determination of the minimum inhibition concentrations (MICs). Unlike CP and CTA, the intercalated silver ions were easily released from MMT by ion-exchange with Na+ and acted as very effective antibacterial substances in the long term. Their bactericidal and bacteriostatic effects were determined. Generally, antibacterial compounds are effective when they are released from an inorganic carrier. Metallic silver was prepared by reduction of intercalated Ag+ with sodium borohydride. Antibacterial effects of metallic silver were not observed.