Multi-molecular logic framework based on Morse code, ASCII logic, and Beale's cipher for advanced crypto-steganography

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Abstract

Molecular information coding (MIC) involves biomolecules to encrypt and transmit messages, remains in its early stages of development. This work presents a versatile molecular integration framework and a proof-of-concept multi-level security system that combines Morse code, ASCII code, and Beale's cipher through molecular logic computing, using a molecular dye-oligonucleotide platform (single-stranded DNA, duplex DNA, stem-loop, and G-quadruplex (G-4) structures). This study demonstrates the integration of nanotechnology with crypto-steganographic methods to visualize and decipher codes, embedding elementary logic operations into molecular signal transduction. Additionally, a graphical user interface (GUI) is developed for classifying elementary logic gates using a decision tree algorithm, providing researchers with an accessible tool for rapid prediction. The Morse code-mediated strategy enables static key generation using dots, dashes, and intervals, and dynamic key generation through a polyalphabetic cipher framework. In parallel, ASCII-based logic gate operations facilitate multi-key decryption of decimal values to recover hidden information. Furthermore, a multilayered hybrid cryptographic technique combining Beale's cipher with Morse code implemented via a pangramic codebook, establishes an exceptionally resistant system against brute-force attacks. These methods provide insights into the evolution of communication and highlight the importance of encryption without relying on highly complex materials or sophisticated instruments.

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ASCII code, Beale’s cipher, crypto-steganography, DNA, graphical user interface, molecular dyes, Morse code

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Small. 2026, vol. 22, issue 23.