Multi-molecular logic framework based on Morse code, ASCII logic, and Beale's cipher for advanced crypto-steganography

dc.contributor.authorMattath, Mohamed Nabeel
dc.contributor.authorLu, Yingying
dc.contributor.authorParambil, Ajith Manayil
dc.contributor.authorGao, Yan
dc.contributor.authorYao, Tian-Ming
dc.contributor.authorLi, Jing-Jing
dc.contributor.authorZang, Rui-Min
dc.contributor.authorHu, Song
dc.contributor.authorShi, Shuo
dc.date.accessioned2026-05-12T13:20:47Z
dc.date.available2026-05-12T13:20:47Z
dc.date.issued2026
dc.description.abstractMolecular information coding (MIC) involves biomolecules to encrypt and transmit messages, remains in its early stages of development. This work presents a versatile molecular integration framework and a proof-of-concept multi-level security system that combines Morse code, ASCII code, and Beale's cipher through molecular logic computing, using a molecular dye-oligonucleotide platform (single-stranded DNA, duplex DNA, stem-loop, and G-quadruplex (G-4) structures). This study demonstrates the integration of nanotechnology with crypto-steganographic methods to visualize and decipher codes, embedding elementary logic operations into molecular signal transduction. Additionally, a graphical user interface (GUI) is developed for classifying elementary logic gates using a decision tree algorithm, providing researchers with an accessible tool for rapid prediction. The Morse code-mediated strategy enables static key generation using dots, dashes, and intervals, and dynamic key generation through a polyalphabetic cipher framework. In parallel, ASCII-based logic gate operations facilitate multi-key decryption of decimal values to recover hidden information. Furthermore, a multilayered hybrid cryptographic technique combining Beale's cipher with Morse code implemented via a pangramic codebook, establishes an exceptionally resistant system against brute-force attacks. These methods provide insights into the evolution of communication and highlight the importance of encryption without relying on highly complex materials or sophisticated instruments.
dc.description.issue13
dc.description.sourceWeb of Science
dc.description.volume22
dc.identifier.citationSmall. 2026, vol. 22, issue 23.
dc.identifier.doi10.1002/smll.202513587
dc.identifier.issn1613-6810
dc.identifier.issn1613-6829
dc.identifier.urihttp://hdl.handle.net/10084/158605
dc.identifier.wos001651509500001
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofseriesSmall
dc.relation.urihttps://doi.org/10.1002/smll.202513587
dc.rights© 2025 Wiley-VCH GmbH
dc.subjectASCII code
dc.subjectBeale’s cipher
dc.subjectcrypto-steganography
dc.subjectDNA
dc.subjectgraphical user interface
dc.subjectmolecular dyes
dc.subjectMorse code
dc.titleMulti-molecular logic framework based on Morse code, ASCII logic, and Beale's cipher for advanced crypto-steganography
dc.typearticle
dc.type.statusPeer-reviewed
dc.type.versionpublishedVersion
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